Brands Names: Adoxa, Doryx, Monodox, Targadox, Vibramycin
Price Range: $0.33 – $0.59
Dosage: 100mg / 200mg
Doxycycline is an antibacterial drug of semi-synthetic origin, which belongs to the tetracycline series of antibiotics. Drugs belonging to this group are active against many pathogenic microorganisms.
Antibiotic Doxycycline demonstrates a wide range of action. Therefore, it is one of the primary drugs used for the treatment of infectious diseases.
Doxycycline is effective in treating many types of pathogenic flora. This medication is primarily prescribed for infections involving aerobic and anaerobic microorganisms.
Doxycycline demonstrates high efficacy in the treatment of diseases caused by streptococcal origins such as staphylococci, salmonella, and E. coli. This medication can also be used to treat such common diseases as cholera, tularemia, plague, and anthrax to which the causative agent is clostridia, a dysentery rod.
Doxycycline is administered orally and is quickly absorbed. Most of the active ingredient is absorbed into the gastrointestinal tract so that the therapeutic effect is quickly achieved. The total concentration of antibiotic is observed two hours following administration.
Forms of Doxycycline
Doxycycline is dispensed in the following dosage forms:
- Tablets are dispensed in 100 mg strength, 10 per pack
- Capsules are made of gelatin. The powder mixture determines the contents of the capsules with the presence of small impregnations of white hue. Five pills are contained per pack
- Liofilizate for injection. This form of Doxycycline is contained in ampoules of 100 mg strength. The drug is dispensed in 5 or 10 ampoules per package
The primary indications for Doxycycline use are:
- Upper and lower respiratory tract infections (e.g., pneumonia, bronchitis, purulent pathologies in the form of pleurisy, abscess, and phlegmon).
- Urinary infection (e.g., cystitis, pyelonephritis, urethritis).
- Otorhinolaryngology diseases (e.g., sinusitis, tonsillitis, frontal sinus, maxillary sinusitis).
- Abnormalities of the intestine (e.g., typhoid fever, escherichia, cholera, dysentery, rotavirus infection, salmonellosis and others).
- Infectious processes affecting the male and female genital organs and excretory system (e.g., prostatitis, endometritis, epididymitis).
- Inflammatory diseases of the digestive tract caused by microorganisms (e.g., peritonitis, enterocolitis, proctitis, cholecyst cholangitis).
- infections of the skin and soft tissues (e.g., carbuncles, furunculosis, acne, phlegmon).
- Infections of genital organs (e.g., chlamydia, syphilis, gonorrhea, herpes, uterine erosion).
- Infectious diseases of the whole organism (e.g., tularemia, whooping cough, fever, typhoid, leptospirosis, and others).
- Ophthalmic pathologies (e.g., ulcerative keratitis, conjunctivitis, chlamydia, trachoma).
- Osteomyelitis, infectious arthritis, and other diseases.
In addition to use in primary treatment, antibiotics are widely used to prevent malaria and negative consequences after an abortion.
- Hypersensitivity to antibacterial agents of the tetracycline group, particularly Doxycycline or its components.
- Low level of leukocytes.
- Lactose intolerance.
- Pathological processes of the liver.
- Children younger than 8 years of age.
- Lupus erythematosus.
- Hereditary disease characterized by impaired absorption of sugar in the body.
- A high value in the blood plasma of porphyrins, which are an important pigment of blood cells.
- Children over 12 years of age if the teenager weighs less than 45 kg.
Side effects of Doxycycline
- Gastrointestinal tract (e.g., nausea, vomiting, loss of appetite, diarrhea)
- Central nervous system (e.g., headaches, dizziness, impaired visual function)
- Hemopoietic system (e.g., reduction of erythrocytes and thrombocytes)
- Increased level of eosinophils and anemia
- Allergic reactions, which are characterized by the development of itching, rashes, hyperemia of the skin
- Intestinal microflora (e.g., dysbacteriosis)
Instructions for use
It is important to always strictly follow prescription guidelines and recommendations when using Doxycycline.
How to take Doxycycline?
Doxycycline is available in several forms and therefore the method of administration may vary. The daily dose of Doxycycline can be taken 1 or 2 times with a 12 hour time interval between doses. The amount of Doxycycline administered is determined by the attending physician and depends on the severity of the disease, pathogen form, and patient age.
Doxycycline tablets can be taken with or without food, but preferably before meals. The typical Doxycycline dose schedule is usually 200 mg on the first day and 100 mg on the remaining days of the therapeutic course. Doxycycline tablets should be washed down with a sufficient amount of water. Children weighing more than 45 kg are prescribed Doxycycline at 4 mg per kg to which the dosage can then be reduced to 2-4 mg.
Instruction for the use of Doxycycline capsules is the same as that of tablets. In cases requiring Doxycycline intravenous injection, a single dosage should not exceed 200 mg. The maximum dose of Doxycycline in oral form is 600 mg.
Treatment during pregnancy
Doxycycline should not be taken during pregnancy because the drug has a negative effect on fetal development. An antibiotic can provoke malfunction of the liver of a future mother, slow the growth of a child, and destroy tooth enamel.
Doxycycline promotes the formation of liver infiltration and poor development of the skeleton of the fetus. Therefore, during the period of gestation, Doxycycline is categorically contraindicated.
Interaction with alcohol
Doxycycline should not be taken while consuming alcohol. If this rule is not observed, it is possible that adverse events will be experienced, which involve dangerous symptoms and abnormal nervous system function. This may include lack of coordination, dizziness, headaches, migraine headaches, nausea, and/or vomiting.
Doxycycline and alcohol consumption exert a heavy load on the liver, increasing the risk of hepatitis and liver failure. The therapeutic effect of this drug may be reduced. To avoid the negative consequences of Doxycycline, it is necessary to abandon any alcohol consumption, even if the drug is used for prevention purposes.