Brands Names: Adoxa, Doryx, Monodox, Targadox, Vibramycin
Price Range: $0.33 – $0.59
Dosage: 100mg / 200mg
Doxycycline is an antibacterial drug of semi-synthetic origin, which belongs to the tetracycline series of antibiotics. The drug of this group is active against many pathogenic microorganisms.
Antibiotic Doxycycline has a wide range of action. Therefore it is one of the primary drugs for the treatment of infectious diseases.
The drug is effective in many types of pathogenic flora, mainly it is prescribed for infection with aerobic and anaerobic microorganisms.
Excellent effect Doxycycline shows in the treatment of diseases caused by streptococcal forms, staphylococci, salmonella and E. coli. It also treats such common diseases as cholera, tularemia, plague and anthrax, the causative agents of which are clostridia, a dysentery rod.
Doxycycline is used orally, and it is quickly absorbed. Most of it is absorbed into the gastrointestinal tract so that the curative effect is achieved quickly. The total concentration of antibiotic is observed after two hours.
Form of Doxycycline
The drug Doxycycline has the following dosage forms:
- Tablets are released in 100 mg form, 10 per pack.
- Capsules are made of gelatin. The powder mixture determines the contents of the capsules with the presence of small impregnations of white hue. In the pack contains five pills.
- Liofilizate for injection. This form of Doxycycline is contained in ampoules of 100 mg. The drug is released for 5 and ten ampoules per package.
The primary indications for use are:
- Upper and lower respiratory tract infections (pneumonia, bronchitis, purulent pathologies in the form of pleurisy, abscess, and phlegmon).
- Urinary infection (cystitis, pyelonephritis, urethritis).
- Otorhinolaryngology diseases (sinusitis, tonsillitis, frontal sinus, maxillary sinusitis).
- Abnormalities of the intestine (typhoid fever, escherichia, cholera, dysentery, rotavirus infection, salmonellosis and others).
- Infectious processes affecting the male and female genital organs and excretory system (prostatitis, endometritis, epididymitis).
- Inflammatory diseases of the digestive tract caused by microorganisms (peritonitis, enterocolitis, proctitis, cholecyst cholangitis).
- The defeat of the skin and soft tissues (carbuncles, furunculosis, acne, phlegmon).
- Infections of the genital organs (chlamydia, syphilis, gonorrhea, herpes, uterine erosion).
- Infectious diseases of the whole organism (tularemia, whooping cough, fever, typhoid, leptospirosis, and others).
- Ophthalmic pathologies (ulcerative keratitis, conjunctivitis, chlamydia, trachoma).
- Osteomyelitis, infectious arthritis, and other diseases.
In addition to the primary treatment, antibiotics are widely used to prevent malaria and negative consequences after an abortion.
Contraindications for use
- Hypersensitivity to antibacterial agents of the tetracycline group, in particular to Doxycycline or its components.
- Low level of leukocytes in the body.
- Lactose intolerance.
- Pathological processes of the liver.
- Women during pregnancy.
- Children younger than eight years of age.
- Lupus erythematosus.
- Hereditary disease characterized by impaired absorption of sugar in the body.
- A high value in the blood plasma of porphyrins, which are an important pigment of blood cells.
- Children over 12 years of age, if the teenager weighs less than 45 kg.
Side effects of Doxycycline
- Gastrointestinal tract (nausea, vomiting, a violation of appetite, diarrhea),
- Central nervous system (headaches, dizziness, impaired visual function),
- Hemopoietic system (reduction of erythrocytes and thrombocytes,
- Increased level of eosinophils and formation of anemia),
- Allergic reactions, that characterized by the development of itching, rashes, hyperemia of the skin,
- Intestinal microflora (dysbacteriosis).
Instructions for use
It is necessary to strictly follow the instructions, namely the dosage, frequency and method of administration of the drug.
How to take Doxycycline?
Since the drug is available in several forms, the method of administration may be somewhat different. The daily dose of the drug is allowed to take for 1 or 2 times, then the interval between doses should be 12 hours. The amount of medicinal substance is determined by the attending physician and depends on the severity of the disease, the form of the pathogen and the age of the patient.
Antibiotic in tablets is used regardless of the time of food intake, but preferably before meals. Usually, the dose is determined by 200 mg in the first day and 100 mg in the remaining days of the therapeutic course. The tablet should be washed down with a sufficient amount of clean water. Children weighing more than 45 kg are prescribed Doxycycline of 4 mg per kg, then the dosage is reduced to 2-4 mg.
Instructions for the use of capsules Doxycycline is similar to the use of tablets. They should also be washed down with a large volume of water, the dose is determined 200 or 100 mg per day, depending on the type of pathogen and the severity of the pathology. In case of intravenous injection of the antibiotic, a single dosage should not be more than 200 mg. The maximum dose of the drug for oral use is 600 mg.
Treatment during pregnancy
Doxycycline during pregnancy cannot be taken because the drug has a negative effect on the fetal development of the fetus. An antibiotic can provoke a malfunction of the liver of a future mother, slow the growth of a child and destroy tooth enamel.
Penetrating deep into the body, Doxycycline promotes the formation of liver infiltration and poor development of the skeleton in the fetus. Therefore, in the period of gestation, the baby is categorically contraindicated.
Interaction with alcohol
Everyone knows that medications cannot be taken with alcoholic beverages, and this drug is no exception. If this rule is not observed, it is possible to develop negative consequences, which are manifested by unpleasant symptoms and more often involve the nervous system. In this case, if there is a development of signs of intoxication, a person begins fell a lack of coordination, dizziness, headaches, migraine headaches, nausea, and vomiting.
Doxycycline and alcohol exert a heavy load on the liver, increasing the risk of hepatitis and liver failure. The therapeutic effect may be reduced. To exclude the negative consequences of the antibiotic, it is necessary to abandon any alcohol, even if the drug is used for prevention purposes.